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CoQ10 and its Benefits

What is CoQ10 and where is it found?

CoQ10 which is short for co-enzyme Q10 or Ubiquinol is a compound found the in human body. It is found in the cell membrane of the mitochondria (the cells “power house”). CoQ10 is an essential component in metabolism; the process that creates energy for the cell to use.[1] Co Q10 is an antioxidant.[2]

The effects of Statins on CoQ10 in the body.

Statins reduce the bodies synthesis of coQ10 [3] by as much as 40%. Side effects of statins as stated on the NHS website [4] include headaches, nausea, joint pains, difficultly sleeping, loss of appetite, vision problems, tinnitus, dizziness and memory loss. Anecdotal evidence suggests that taking a supplement of CoQ10 can help control some side effects and reduce blood pressure. [5] Trials are limited to determine whether these results are significant or not. However some trials are, check them out below.

Where is the evidence that CoQ10 works?

Mortensen & Kumar (2013) in a 2 year study of heart disease patients found that mortality rates were cut in half when CoQ10 was administered.[6]Molyneux & Florkowski (2008) found that low levels of CoQ10 in chronic heart disease patients indicated a higher mortality rate. [7] Sándor & Clemente (2005) Studies into relieving migraines with CoQ10 have been positive.[8]

 

How can I take CoQ10?

You can get CoQ10 from your diet, most notably beef, pork chicken and fish – in that order, but it is also available in smaller amounts soybeans, olives, grapeseed, sesame seeds, parsley and avocado. Frying reduces the amounts of CoQ10 in your food by up to 32%.[9]CoQ10 is better absorbed with food and in the presence of lipids (fats). Most Co Q 10 capsules contain oils to aid in absorption.

[1] Tortora & Grabowski. Principles of Anatomy and Physiology. 8th Edition Benjamin Cummings: Harlow, England (2006)

 

[2] http://www.umm.edu/altmed/articles/coenzyme-q10-000295.htm

 

[3] Ghirlanda, et al., "Evidence of plasma CoQ10-lowering effect of HMG-COA reductase inhibitors: a double-blind, placebo-controlled study," Journal of Clinical Pharmacology. 1993 Mar; 33(3):226-229.

 

[4] http://www.nhs.uk/Conditions/Cholesterol-lowering-medicines-statins/Pages/Side-effects.aspx

 

[5] http://www.cholesterol-and-health.com/Coenzyme-Q10.html

 

[6] SA Mortensen, A Kumar, P Dolliner, et al. (May 2013). "The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure. Results from the Q-SYMBIO study.". Heart Failure Congress 2013 Final Programme Number 440.

 

[7] Molyneux SL, Florkowski CM, George PM, et al. (October 2008). "Coenzyme Q10: an independent predictor of mortality in chronic heart failure". J. Am. Coll. Cardiol. 52 (18): 1435–41. doi:10.1016/j.jacc.2008.07.044. PMID 19017509.

 

[8] Sándor, PS; Di Clemente, L; Coppola, G; Saenger, U; Fumal, A; Magis, D; Seidel, L; Agosti, RM et al. (2005). "Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial". Neurology 64 (4): 713–5. doi:10.1212/01.WNL.0000151975.03598.ED. PMID 15728298.

 

[9] Weber, C; Bysted, A; Hłlmer, G (1997). "The coenzyme Q10 content of the average Danish diet". Int J Vitam Nutr Res 67 (2): 123–9. PMID 9129255.

 

 

Posted by Country Kitchen on 09 March 2018 13:18

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